COMPLEX SOLUTIONS FOR MOLECULAR BIOLOGICAL RESEARCH

DNA Extraction:

• Cells, eukaryotic: blood cells, cultured cells, tissue cells (fresh/frozen), pathogens
• Cells, prokaryotic: bacteria, virus
• FFPE
• Body fluids: serum, plasma, urine, cell media, buccal swabs, saliva, cerebral spinal fluid, stool, and other cell-free body fluids
• Environmental samples
• Plants
• Ancient materials
• Other

RNA Extraction:

• Cells, tissue
• Blood
• Biofluids (e.g., plasma, serum)
• Formalin-fixed, paraffin-embedded (FFPE), laser capture microdissection (LCM), fine needle aspirate biopsies (FNAB)
• Others

We support high-throughput intake, standardized labeling, and secure sample storage with optional integrity checks.

• Quantification and purity assessment
• Short- and long-term sample archiving
• Custom collection kits on request

• Whole Genome Sequencing
• Exome Sequencing
• Targeted Sequencing
• Amplicon Sequencing
• RNA Sequencing
• Diseases focused panels
• Others

We offer many different library preparation options:

• Fast turnaround times
• Ultra-low requirements
• Barcoded libraries
• Pooled libraries
• QC control
• Dry ice delivery
• Library storage

We provide pre- and post-library QC summaries and can align workflows to your downstream sequencing requirements.

• Input and library integrity checks
• Standardized reporting and documentation
• Consultation on assay design

PCR product, purified or unpurified. Plasmid, purified or bacterial clones. Optional template purification. Single-read service (96-well format only), verification sequencing. Outstanding data quality with fast delivery.

The data included in our reports for every sequence are Phred20 analysis, *.ABI and *.scf trace files and seq files in text format. Verification sequencing reports provide the following: insertions, deletions, mismatches between reference sequence and sequencing data, and alignment between reference sequence and sequencing data.

Sanger sequencing is used to study a small subset of genes linked to a defined phenotype, confirm next-generation sequencing (NGS) variants, detect minor allele fractions down to 5%, or read contiguous sequences up to 1,000 bases.

Fragment analysis is a powerful technique with simple, straightforward workflows and used in a wide-range of applications, such as detection of mutations, genotyping, identification of short tandem repeats, and gene expression profiling. We use Applied Biosystems genetic analysis systems - a trusted standard for Sanger sequencing and fragment analysis by capillary electrophoresis.

• Standard deliverables include trace files and QC notes
• Clear alignment summaries against reference sequences
• Turnaround options for priority samples

• Whole Genome Sequencing (WGS)
• Whole Exome Sequencing (WES)
• Targeted Sequencing/Panels (TCS)
• RNA sequencing and Spatial transcriptomics
• Single-cell sequencing
• Metagenomics

• Epigenomics
• Agrigenomics
• Genotyping by sequencing (GBS) services for SNP discovery
• ChIP-Seq
• Amplicon Sequencing
• MethylSeq

GenoMed laboratory operates a suite of sequencing instruments, including Illumina MiSeq and NextSeq 500, MGI and 10x Genomics Chromium. We provide sequencing as a service to external researchers on unlimited basis.

Our genome sequencing service helps meet a wide range of research goals. Whole Genome Sequencing (WGS) can be applied in disease research as well as in population evolution studies. Target Capture Sequencing (TCS) can be effectively utilized for the in-depth analysis of exons (protein-coding regions of the genome) and genes of interest. As De novo sequencing offers genome assembly and annotation for seldom studied species and species with incomplete reference genomes, it provides a great advantage for plant, animal, and microbial evolution research. We accept ready for sequencing libraries and provide fast and accurate sequencing. One library or hundreds of libraries - it is all possible.

• Flexible project sizes with batch scheduling
• Secure data transfer and storage options
• Bioinformatics support available on request

• Human Genotyping
• Non-Human Genotyping
• Methylation Analysis
• Genome-Wide Genotyping
• Targeted Genotyping

• Custom Genotyping
• Cytogenetic/copy number analysis
• Pharmacogenomics
• Microbiome Solutions
• Transcriptome profiling

Microarrays are the best technique for genotyping and gene expression solution for many species.

The Axiom Genotyping Solution provide researchers with powerful genotyping tools to identify, validate, and screen complex genetic traits in human, plants, animals or micobes. It includes arrays with genotype-tested content from the Axiom Genomic Database or de novo markers that are important to you. The complete solution comprises genotyping arrays, reagent kits, a fully automated workflow, and easy-to-use free data analysis tools. Customize your genotyping array or panel for any high-throughput industrial application with confidence that all of your markers of interest can be targeted and manufactured on the custom array.

• QC metrics and call rate summaries
• Raw and processed data files on delivery
• Consultation on array design and content

• Biobanking
• DNA storage
• Bioinformatics
• Targeted sequencing panels design

• Cell cultivation
• Cytogenetic
• Metabolomic and proteomic
• Consulting

Our life science laboratory services provide you with an international reach and employ the latest technology and methodologies - so that you get the most accurate and reliable results. Our expert staff is trained to the highest standards and has an in-depth knowledge of their fields and your business needs. We provide experience in meeting both international and local regulations for a wide range of industries.

• Regulatory and documentation support
• Custom workflow design and optimization
• Logistics coordination for regional partners

Panorama test, NATERA, USA

Panorama is a blood-based genetic, prenatal screening test of the pregnant mom that screens for common chromosomal conditions that affect a baby's health. Panorama uses unique SNP-based technology to deliver the most accurate non-invasive prenatal testing on the market. Panorama can be performed as early as nine weeks gestation. Most results will be returned to your doctor within 5-7 calendar days.

NIFTY test, BGI, China

NIFTY is a highly accurate, non-invasive prenatal screening that uses a blood sample from the pregnant mother to detect chromosomal abnormalities in the fetus. NIFTY is available from as early as the 10th week of pregnancy and can screen for a range of chromosomal abnormalities in both singleton and twin pregnancies, such as Down Syndrome (Trisomy 21) and Edwards Syndrome (Trisomy 18), and other chromosomal abnormalities that could affect a baby's health.

• Early gestation screening pathways
• Support for singleton and twin pregnancies
• Clinical guidance and reporting support

Sequencing, data analysis, varialt calling, ACMG classification and clinical interpretation according to patient phenotype.

• Phenotype-driven variant prioritization
• ACMG classification and clinical reporting
• Secure data handling and delivery

• Preimplantation genetic testing "PGT-A"
• Preimplantation genetic testing "PGT-SNP"
• Non-invasive preimplantation genetic testing "niPGT"
• Determining the relationship of the embryo

• Establishing the origin of the chromosomal imbalance found in the embryo
• Analysis of endometrial receptivity "ERT-test"
• Preimplantation genetic diagnosis of monogenic diseases (PGT-M)
• Non-invasive preimplantation genetic testing "PGT-A + niPGT"

Pre-implantation Genetic Testing (PGT) is a sophisticated scientific technique which can be used to test embryos for either a specific known single gene condition or chromosome variation.

This enables only chromosomally healthy embryos or those unaffected by a specific disorder to be selected for transfer during an IVF cycle, maximising the chance of a healthy baby.

Increased Detection Rates. Faster Results at Lower Costs. Streamlined Processes. Support from Sample-to-result.

• Sample-to-result workflow support
• Embryo selection guidance for clinicians
• Documentation for IVF cycle planning

Postnatal diagnostics microdeletion syndromes. Prenatal diagnostics microdeletion syndromes. Miscarriage diagnostics. Loss of heterozygosity detection and Uniparental disomy diagnostics.

The innovative oligonucleotide-based microarrays, these solutions have been specifically designed, developed and validated by cytogeneticists for cytogeneticists performing molecular karyotyping.

Molecular cytogenetics plays an important role in the characterization of chromosome anomalies and is a critical component of current genetic studies including research into both constitutional disorders and cancer. GenoMed is bringing the newest molecular techniques to cytogenetic laboratories. Our innovative methodologies support:

• Microdeletion and microduplication profiling
• Prenatal and postnatal diagnostic workflows
• Validated reporting for clinical cases

Screening Diagnosis and Prognosis

Treatment PlanningMonitoring

GenoMed is determined to help you identify the ideal treatment path using the right test so you can deliver the best possible outcomes based on the most relevant data.

• Screening and early detection pathways
• Therapy selection and response tracking
• Longitudinal monitoring and follow-up

Wellness and Nutrition test. Pharmacogenetics. Inherited diseases carrier screening. Fertility test. Paternity test.

Ancestry test. Fluorescent hybridization in situ (FISH). Immunohistochemistry (IGH). Anatomical pathology tests. Allergy tests.

• Wellness and Nutrition test
• Pharmacogenetics
• Inherited diseases carrier screening
• Fertility test
• Paternity test
• Ancestry test
• Fluorescent hybridization in situ (FISH)
• Immunohistochemistry (IGH)
• Anatomical pathology tests
• Allergy tests

Clinical portfolios can be tailored by region or specialty to align with local regulations and referral pathways.